Synulox RTU Injection 40ml

4.1 Target species Cattle, pigs, dogs and cats. 4.2 Indications for use, specifying the target species This product has bactericidal activity against a broad spectrum of clinically important bacteria found in large and small animals. In vitro the product is active against a wide range of bacteria, including strains resistant to amoxicillin alone because of beta-lactamase production: Gram-positive Actinomyces bovis Bacillus anthracis Clostridia Corynebacteria Peptostreptococcus spp. Staphylococci Streptococci Gram-negative Actinobacillus lignierisi Actinobacillus pleuropneumoniae Bacteroides Bordetella bronchiseptica Campylobacter spp. Escherichia coli Fusobacterium necrophorum Haemophilus spp. Klebsiellae Moraxella spp. Pasteurellae Proteus spp. Salmonellae Clinically the product is indicated for the treatment of diseases including: Cattle Respiratory infections, soft tissue infections (e.g. joint-ill/navel-ill, abscesses etc.), metritis and mastitis. Combined Therapy for the treatment of bovine mastitis: In the situation where systemic treatment as well as intramammary treatment is necessary, Synulox Ready-to-Use injection can be used in combination with Synulox Lactating Cow Intramammary. Pigs Respiratory bacterial infections in growing pigs. Colibacillosis. Periparturient infections in sows (e.g. mastitis, metritis and agalactia.) Dogs and Cats Respiratory tract infections, urinary tract infections and skin and soft tissue infections (e.g. abscesses, pyoderma, anal sacculitis, gingivitis). 4.3 Contraindications The product should not be administered to rabbits, guinea pigs, hamsters or gerbils. Caution is advised in its use in other very small herbivores. 4.4 Special warnings for each target species None. 4.5 Special precautions for use i) Special precautions for use in animals Care should be taken to avoid contaminating the remaining contents of a vial with water. Clavulanic acid is moisture sensitive. It is very important that a completely dry syringe is used when extracting the suspension for injection in order to avoid contaminating the remaining contents of the vial with drops of water. Contamination will result in obvious beads of dark brown discolouration corresponding to the introduced water droplets. Material affected in this way should not be used as it may have significantly reduced potency. ii) Special precautions to be taken by the person administering the veterinary medicinal product to animals Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious. Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations. Handle this product with great care to avoid exposure, taking all recommended precautions. If you develop symptoms following exposure such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing, are more serious symptoms and require urgent medical attention. Wash hands after use. 4.6 Adverse reactions (frequency and seriousness) Use of the product may occasionally result in pain on injection and/or local tissue reactions. 4.7 Use during pregnancy, lactation or lay The product may be used in pregnant animals, subject to observance of the withholding time for milk and the withdrawal time for meat intended for human consumption. 4.8 Interaction with other medicinal products and other forms of interaction None known.