Target species Dogs. Indications for use 1Treatment of behavioural disorders of purely emotional origin: depression, anxiety. 2In association with behaviour therapy, treatment of signs of emotional origin observed in behavioural conditions such as over activity, separation problems, generalised phobia and unsociable behaviour. Emotional disorders are characterised by a modification of feeding, drinking, auto-stimulatory behaviour, sleep, exploratory behaviour, aggression related to fear and/or irritation, social behaviour and somatic disorders (tachycardia, emotional micturition) Contraindications Owing to its IMAO properties, (–) selegiline hydrochloride may act on prolactin secretion. In the absence of specific studies, it is recommended that the product should not be administered to pregnant and lactating bitches. Do not administer the product from the day before until the day after anaesthesia or tranquillisation performed with an alpha-2 agonist. Do not administer the product concomitantly with pethidine, fluoxetine or phenothiazines. The narcotic action of morphine is potentiated by the product. Special warnings for each target species If no clinical improvement is observed after 2 months, continuing the treatment is not likely to provide any additional benefit. It is advisable to weigh animals before dosing to ensure the correct mg/kg dosage is administered. Special precautions for use, including special precautions to be taken by the person administering the medicinal product to animals Special precautions for use in animals Emotional disorders can mask hierarchical conflicts. In dominant dogs suffering from an emotional disorder, the alleviation of the disorder can sometimes reveal a latent aggressiveness. In such cases, behavioural therapy must be instituted. Special precautions to be taken by the person administering the medicinal product to animals: In the event of accidental ingestion, seek medical advice and show the doctor the package leaflet. Wash hands after use. Adverse reactions (frequency and seriousness) Trials have shown that some dominant dogs, with behavioural disorders but no signs of aggression, may become aggressive after treatment. Those previously showing aggression may have this enhanced. Appropriate training is essential in such cases. Use during pregnancy, lactation or lay It is recommend to stop the treatment during pregnancy and lactation. Interaction with other medicinal products and other forms of interaction Do not administer the product from the day before until the day after an anaesthesia or tranquillisation performed with an alpha-2 agonist. Do not administer the product concomitantly with pethidine, fluoxetine or phenothiazines. The narcotic action of morphine is potentiated by the product.