Relaquine Gel 10ml

Target species Horse. Indications for use For sedation of horses. Contraindications Do not use in cases of post-traumatic shock or hypovolaemia. Do not use in animals in a state of severe emotional excitation. Do not use in animals with epilepsy. Do not use in pregnant or lactating mares. Do not use in animals with heart failure. Do not use in animals with haematological disorders/coagulopathies. Do not use in animals suffering from hypothermia. Do not use in the case of known hypersensitivity to the active substance or any of the excipients of the product. Do not use in neonates. Special warnings for each target species Sedation lasts for approximately six hours, although the actual time and depth of sedation are very dependent on the status of the individual animal. Increasing the dosage above that recommended results in prolonged action and side effects but no greater sedation. Special precautions for use in animals In stallions, the lowest dose range is indicated to minimise prolapse of the penis. The product should be used with caution and with reduced dosage in the case of cardiac or hepatic disease or in debilitated, hypovolemic or anaemic animals. Acepromazine has negligible analgesic effects. Painful activities should be avoided when handling tranquilised animals. Tranquilised horses should be kept in a calm place and sensorial stimuli should be avoided as far as possible. Special precautions to be taken by the person administering the veterinary medicinal product to animals Wash hands and exposed skin thoroughly after use. Persons with sensitive skin or in continuous contact with the product are advised to wear impermeable gloves. Avoid contact with eyes. If accidental eye contact occurs, flush gently with running water for 15 minutes and seek medical advice if any irritation persists. In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician but, DO NOT DRIVE as sedation can occur. Adverse reactions The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals displaying adverse reaction(s) during the course of one treatment) - common ( more than 1 but less than 10 animals in 100 animals) - uncommon (more than 1 but less than 10 animals in 1,000 animals) - rare (more than 1 but less than 10 animals in 10,000 animals) - very rare (less than 1 animal in 10,000 animals, including isolated reports). Since acepromazine decreases sympathetic nervous system tone, a transient drop in blood pressure may occur after administration. Inhibition of temperature regulation. The following reversible changes are possible in the haemogram: - transient decrease in erythrocyte count and haemoglobin concentration; - transient decrease in thrombocyte and leukocyte counts. Because it increases prolactin secretion, the administration of acepromazine may lead to disturbances in fertility. Penile prolapse may occur due to the relaxation of the retractor penis muscles. Retraction of the penis should be visible within two to three hours. If this does not take place, it is advised to contact a veterinary surgeon. Lack of retraction is of particular concern in breeding stallions. Acepromazine has caused paraphimosis sometimes in sequel to priaprism. In rare cases paradoxical excitation reactions can develop. Contradictory clinical signs of aggressiveness and generalised CNS stimulation may occur. Prolapse of the nictitating membrane has also been cited as a possible adverse effect in horses. Use during pregnancy and lactation Acepromazine should not be used in pregnant or lactating mares. Acepromazine has the potential to induce hypotension in newborns when administered as a premedication for caesarean section in the mare. Please see also Adverse reactions relating to disturbances in fertility. Interactions Acepromazine potentiates the action of centrally depressant drugs. Simultaneous administration, or administration to horses recently treated with organophosphates should be avoided since these molecules enhance the toxic effects of acepromazine. Since acepromazine decreases sympathetic nervous system tone, simultaneous treatment with blood pressure lowering products should not take place. Antacids may cause a decrease in the gastrointestinal absorption of acepromazine after oral administration. Opiates may enhance the hypotensive effects of acepromazine.
Vat Rate: 20%