Noroclav 250mg 250 pack

Target species Dogs. Indications for use, specifying the target species Treatment of the following infections caused by β lactamase producing strains of bacteria sensitive to amoxicillin in combination with clavulanic acid: •Skin infections (including superficial and deep pyodermas) caused by susceptible Staphylococci •Urinary tract infection caused by susceptible Staphylococci or Escherichia coli •Respiratory infections caused by susceptible Staphylococci •Enteritis caused by susceptible Escherichia coli It is recommended to carry out suitable tests for sensitivity testing when initiating the treatment. The treatment should only proceed if sensitivity is proven to the combination. Contraindications Do not use in animals with known hypersensitivity to penicillin or other substances of the beta-lactam group. Do not use in rabbits, guinea pigs, hamsters or gerbils. Do not use in animals with serious dysfunction of the kidneys accompanied by anuria and oliguria. Do not use where resistance to this combination is known to occur. Special Warnings for each target species None. Special precautions for use Special precautions for use in animals Inappropriate use of the product may increase the prevalence of bacteria resistant to amoxicillin/clavulanic acid. In animals with hepatic and renal failure, the dosing regimen should be carefully evaluated. Use of the product should be based on susceptibility testing and take into account official and local antimicrobial policies. Narrow spectrum antibacterial therapy should be used for first line treatment where susceptibility testing suggests likely efficacy of this approach. Caution is advised in the use in small herbivores other than those in section, Contraindications. Do not administer to horses and ruminating animals. Special precautions to be taken by the person administering the veterinary medicinal product to animals Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross-reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious. Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations. Handle this product with great care to avoid exposure, taking all recommended precautions. If you develop symptoms following exposure such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms and require urgent medical attention. Wash hands after use. Adverse reactions (frequency and seriousness) Hypersensitivity reactions unrelated to dose can occur with these agents. Gastrointestinal symptoms (diarrhoea, vomiting) may occur after administration of the product. Allergic reactions (e.g. skin reactions, anaphylaxia) may occasionally occur. In case of occurrence of allergic reaction, the treatment should be withdrawn. Use during pregnancy, lactation or lay Studies in laboratory animals have not produced any evidence of teratogenic, effects. Use only according to the benefit/risk assessment by the responsible veterinarian. Interaction with other medicinal products and other forms of interaction Chloramphenicol, macrolides, sulfonamides and tetracyclines may inhibit the antibacterial effect of penicillins because of the rapid onset of bacteriostatic action. The potential for allergic cross-reactivity with other penicillins should be considered. Penicillins may increase the effect of aminoglycosides.