Neopen Suspension for injection 100ml

Target species Horses, sheep, pigs, dogs and cats 4.2 Indications for use, specifying the target species For the treatment of infectious diseases in horses, sheep, pigs, dogs and cats caused by bacteria sensitive to the combination. Penicillin is active against some Gram-negative and most Gram-positive bacteria. Neomycin is a broad spectrum antibiotic active against a number of Gram-positive and Gram-negative bacteria. The combination shows a broad spectrum of activity. In vitro activity has been demonstrated against all tested isolates of E. rhusiopathiae, Streptococcus spp. and A. pyogenes and the majority of tested isolates of Pasteurella, Salmonella, Klebsiella and Staphylococcus species. 4.3 Contra-indications Not to be used in animals known to be hypersensitive to Beta-lactam antibiotics. 4.4 Special warning for each target species None known 4.5 Special precautions for use (i) Special precautions for use in animals See 4.3 above. Shake container before use. (ii) Special precautions to be taken by the person administering the medicinal product to the animals Care should be taken to avoid accidental self-injection. Penicillin and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillin may lead to cross sensitivity to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious. 1. Do not handle this product if you know you are sensitised or if you have been advised not to work with such preparations. 2. Handle this product with great care to avoid exposure, taking all recommended precautions. 3. If you develop symptoms following exposure, such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms and require urgent medical attention. Wash hands after use. 4.6 Adverse reactions (frequency and seriousness) Overdosage with neomycin parenterally can cause renal damage and deafness, but this is unlikely at normal therapeutic dosage levels. Care should be taken in young animals, particularly puppies, kittens and piglets, to ensure accurate computation of dose. Courses of this product should be restricted to a period of three days. Occasionally in sucking and fattening pigs, administration of this product may cause a transient pyrexia, vomiting, shivering, listlessness and incoordination. Additionally in pregnant sows and gilts, a vulval discharge which could be associated with abortion has been reported. Local reaction (swelling) may occur at the injection site in horses for up to a week after administration. Doses exceeding 15 ml should be divided between two injection sites. 4.7 Use during pregnancy or lactation The product is not contra-indicated, but see 4.6 above. The balance of risks should be considered carefully prior to use. 4.8 Interaction with other medicinal products and other forms of interaction Synergism occurs between beta-lactam antibiotics and amino-glycosides. Penicillin exerts its bactericidal action by inhibition of bacterial call wall synthesis during multiplication. It is therefore in principle not compatible with bacteriostatic antibiotics (tetracyclines, chloramphenicol) which inhibit multiplication.
Vat Rate: 20%