Lactovac Suspension for injection for Cattle 25ml (5 dose)

   Product Ref: HOLAC03 Category: L

Temporarily Out of Stock



Target species Cattle (cows and heifers). 4.2 Indications for use, specifying the target species For the active immunisation of pregnant cows and heifers in order to confer passive protection to their calves (via colostrum) to reduce the severity and duration of neonatal diarrhoea caused by rotavirus, coronavirus and E.coli infections. Protection is conferred only while the calves are fed colostrums from vaccinated cows. 4.3 Contraindications Do not use in animals, which have intercurrent infection, or are in poor nutritional status. 4.4 Special warnings for each target species Protection of the herd. Neonatal diarrhoea in calves is caused by pathogens which are constantly present in the herd. For this reason proper control measures require that all pregnant cows and heifers in a herd must be included in the programme of immunisation. This is the only way in which the pressure of infection can be reduced. Herd hygiene Neonatal diarrhoea in calves is often associated with poor hygiene. Thus, general improvements in hygiene are important to support the effect of vaccination. Immune protection Diarrhoeal diseases can have many causes. The vaccine induces high levels of antibody in the colostrum and milk against rotavirus and coronavirus as well as against E.coli, i.e. against the principal pathogens of neonatal diarrhoea in calves. 4.5 Special precautions for use Special precautions for use in animals Only vaccinate immuno-competent animals. Special precautions to be taken by the person administering the veterinary medicinal product to animals In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician. People with known hypersensitivity to any of the components of the product should administer the product with caution. 4.6 Adverse reactions (frequency and seriousness) Immunisation may rarely result in temporary swellings at the injection site (ranging from small nodules of approximately 1cm in diameter to swellings of 20 cm diameter in extreme cases). Typically, these swellings completely disappear or reduce to a negligible size within 2-4 weeks after vaccination, though in individual animals very small reactions remain longer. Additionally, a transient slight rise in body temperature normally decreasing to non-significant level within one day may be expected. The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals displaying adverse reaction(s) during the course of one treatment) - common (more than 1 but less than 10 animals in 100 animals) - uncommon (more than 1 but less than 10 animals in 1,000 animals ) - rare (more than 1 but less than 10 animals in 10,000 animals) - very rare (less than 1 animal in 10,000 animals, including isolated reports) 4.7 Use during pregnancy lactation or lay Can be used during pregnancy. 4.8 Interaction with other medicinal products and other forms of interaction No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Vat Rate: 20%

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Category POM-VPS
Temperature Refrigerated
MA/VM/EU No: 42058/4075
Species
  • cattle
VMD Link https://www.vmd.defra.gov.uk/ProductInformationDatabase/product/A003219
NOAH Link https://www.noahcompendium.co.uk/?id=-457603&fromsearch=true#iosfirsthighlight
Dosage Immunising dose: 5ml Method of administration: Subcutaneous injection into the side of the neck. Basic immunisation: All cows in a herd should receive two injections of 5ml during the later stages of pregnancy, with an interval of 4-5 weeks between doses and allowing 2-3 weeks from the time of the second dose until the predicted date of calving. Booster injection: During each subsequent pregnancy previously vaccinated cows should receive a single injection of 5ml 2-6 weeks prior to the predicted calving date. Passive immunisation of the calves: In order to attain local passive immunisation within the intestine against neonatal diarrhoea, the newborn calves must receive sufficient quality colostrum and milk from the vaccinated dams during the first 10 to 14 days of life. For calves born to beef cows this can be achieved by allowing the calf to suckle naturally. Calves born to dairy cows often do not receive sufficient colostrum if suckled naturally, so artificial feeding of colostrum (e.g. via oesophageal tube feeders) should be used. Feeding and storage of colostrum For optimal protection it has been shown that the daily intake of colostrum is essential to the calf from birth to 2 weeks of age. All calves should be fed colostrum derived from the first milking, ideally within the first 6 hours of life. Calves should then either be left to suckle naturally for a minimum of 2 weeks or a colostrum feeding regime must be established. Any remaining quantities from the first milking and all the colostrum from the second milking should be pooled, aliquoted and stored deep frozen (-20 o C for maximal one year). Alternatively, these colostrum pools can be stored at about +4oC for about 2 weeks. Following the first suckling of colostrum from the dam by the calves, where the calves are separated from the dam, their feed must be supplemented with 500 ml of pooled colostrum each day. 4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary Accidental overdosage is unlikely to cause any reaction other than those described in section 4.6.
Withdrawals Zero days.