Ketofen 10% solution for injection 100ml

Target species Horses, cattle, pigs. Indications for use, specifying the target species In the horse, Ketofen 10% is indicated for: -The alleviation of inflammation and pain associated with musculoskeletal disorders; -The alleviation of visceral pain associated with colic. In cattle, Ketofen 10% is indicated for: -The supportive treatment of parturient paresis associated with calving; -Reducing the pyrexia and distress associated with bacterial respiratory disease when used in conjunction with antimicrobial therapy as appropriate; -Improving the recovery rate in acute clinical mastitis, including acute endotoxin mastitis, caused by gram negative micro-organisms, in conjunction with antimicrobial therapy; -Reducing oedema of the udder associated with calving; -Reducing pain associated with lameness In pigs, Ketofen 10% is indicated for: -Reducing the pyrexia and respiratory rate associated with bacterial or viral respiratory disease when used in conjunction with antimicrobial therapy as appropriate; -The supportive treatment of Mastitis Metritis Agalactia Syndrome in sows, in conjunction with antimicrobial therapy as appropriate. Contraindications Do not administer to horses, cattle or pigs that have previously shown a hypersensitivity to ketoprofen. Do not administer other non-steroidal anti-inflammatory drugs (NSAIDs) concurrently or within 24 hours of each other. Use is contraindicated in animals suffering from cardiac, hepatic or renal disease, where there is the possibility of gastrointestinal ulceration or bleeding, where there is evidence of a blood dyscrasia or hypersensitivity to the product. Special warnings for each target species Use in any animal less than 6 weeks of age or in aged animals may involve additional risk. If such use cannot be avoided animals may require a reduced dosage and careful management. Avoid use in any dehydrated, hypovolaemic or hypotensive animals as there is a potential risk of increased renal toxicity. Special precautions for use Special precautions for use in animals Avoid intra-arterial injection. Do not exceed the stated dose or duration of treatment. Special precautions to be taken by the person administering the medicinal product to animals In case of accidental self-injection seek medical advice. Wash hands after use. Avoid splashes on the skin and eyes. Irrigate thoroughly with water should this occur. If irritation persists seek medical advice. Adverse reactions (frequency and seriousness) In common with all NSAIDs, due to their action of inhibition of prostaglandin synthesis, there can be the possibility in certain individuals of gastric or renal intolerance. Use during pregnancy, lactation or lay As the effects of ketoprofen on fertility, pregnancy or foetal health of horses have not been determined, Ketofen 10% should not be administered to pregnant mares. Ketofen 10% may be given to pregnant and lactating cattle. It is indicated for use in lactating sows. Interaction with other medicinal products and other forms of interaction Some NSAIDs may be highly bound to plasma proteins and compete with other highly bound drugs which can lead to toxic effects. Concurrent administration with nephrotoxic drugs should be avoided.