Gonavet Veyx 50micrograms/ml solution for injection 10ml POM by vet pharmacy online

Product Ref: APGON01 Category: G

Price

€ 36.72

Vat Rate: 20%

Qty

Prescription Required

4. CLINICAL PARTICULARS 4.1 Target species Cattle (cows, heifers), pigs (sows, gilts), horses (mares) 4.2 Indications for use, specifying the target species Control and stimulation of reproduction in cattle and pigs. Treatment of ovarian-related fertility disorders or dysfunctions in cattle and horses. Cattle (cows, heifers):  Ovulation induction in case of delayed ovulation due to LH-deficiency  Induction/synchronization of ovulation within the framework of systems for timed inseminations  Stimulation of the ovaries during the puerperal period from day 12 post partum  Ovarian cysts (due to LH-deficiency) Pigs (sows, gilts):  Induction/synchronization of ovulation within the framework of systems for timed insemination and parturition synchronization Horses (mares):  Acyclia and anoestrus due to LH-deficiency 4.3 Contraindications Do not use in cows with a mature tertiary follicle ready to ovulate. Do not use during infectious diseases and other relevant health disorders. Do not use in cases of known hypersensitivity to the active substance or to any of the excipients. 4.4 Special warnings for each target species To maximise conception rates of cows to be treated with GnRH-PGF2α based synchronization protocols, the ovarian status should be determined and regular cyclic ovarian activity confirmed. Optimal results will be achieved in healthy normally cycling cows. 4.5 Special precautions for use Special precautions for use in animals None. Special precautions to be taken by the person administering the veterinary medicinal product to animals Administration should be performed with caution in order to avoid accidental self-injection. In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician. As GnRH analogues can be absorbed through the skin, accidental spillage onto skin or into the eyes should be thoroughly rinsed off with water. The veterinary medicinal product should not be administered by pregnant women. Women of child-bearing potential should administer the product with caution. People with known hypersensitivity to GnRH should avoid contact with the veterinary medicinal product. 4.6 Adverse reactions (frequency and seriousness) None known. 4.7 Use during pregnancy, lactation or lay Pregnancy: Not applicable. Lactation: Can be used during lactation. 4.8 Interaction with other medicinal products and other forms of interaction A synergistic effect occurs in case of combined administration with FSH, especially in case of a disturbed puerperal course. Simultaneous use of human or equine chorionic gonadotropin may lead to ovarian over-stimulation.
Vat Rate: 20%

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Category	POM-V
Temperature	Refrigerated
MA/VM/EU No:	27569/4005
Species	cattle horse pig
VMD Link	Product Information Database (defra.gov.uk)
NOAH Link
Dosage	4.9 Amounts to be administered and administration route For intramuscular or subcutaneous injection. For intramuscular use, preferably in the neck region. The product is intended for single administration except when used as part of the “Ovsynch” timed artificial insemination protocol. Dosage in ml product and micrograms Gonadorelin[6-D-Phe] per animal. Cattle (cows and heifers) by intramuscular injection: 1.0 - 2.0 ml (corresponding to 50 – 100 micrograms of Gonadorelin[6-D-Phe]) - Ovulation induction in case of delayed ovulation due to LH-deficiency 2.0 ml - Induction/synchronization of ovulation within the framework of systems for timed inseminations 1.0 - 2.0 ml - Stimulation of the ovaries during the puerperal period from day 12 post partum 1.0 ml - Ovarian cysts (due to LH-deficiency) 2.0 ml Pigs (sows and gilts) by intramuscular or subcutaneous injection: 0.5 - 1.5 ml (corresponding to 25 – 75 micrograms of Gonadorelin[6-D-Phe]) - Induction/synchronization of ovulation within the framework of systems for timed inseminations and parturition synchronization Sows: 0.5 - 1.0 ml Gilts: 1.0 - 1.5 ml Horses (mares) by intramuscular injection: 2.0 ml (corresponding to 100 micrograms of Gonadorelin[6-D-Phe]) The rubber stopper of the vial may be safely punctured up to 25 times. Otherwise, automatic syringe equipment, or a suitable draw-off needle, should be used for the 20 ml and 50 ml vials to avoid excessive puncturing of the closure. Special information Cattle: For oestrus and ovulation synchronization and timed artificial insemination (AI) in cattle the so called “Ovsynch-procedure” was developed, which consists of the combined use of GnRH and PGF2α. The following timed AI protocol has been commonly reported in the literature: Day 0: Inject 100 micrograms of Gonadorelin6-D-Phe per animal (2 ml of the product) Day 7: Inject PGF2 or analogue (luteolytic dose) Day 9: Inject 100 micrograms of Gonadorelin6-D-Phe per animal (2 ml of the product) AI: 16 – 20 hours later, or at observed oestrus if sooner The Ovsynch-procedure may not be as efficacious in heifers as in cows. Pigs: The ovulation synchronization system includes the administration of Peforelin or PMSG after the end of oestrus synchronisation with Altrenogest in gilts or after the weaning in adult sows and two timed artificial inseminations. In adult sows the time table depends on the duration of the suckling period. The following procedures are recommended: Gilts* Adult sows** Induction of oestrus Peforelin 48 h or PMSG (eCG) 24 h - 48 h after last application of Altrenogest Peforelin or PMSG application 24 h after weaning Synchronization of ovulation Gonadorelin6-D-Phe 78 - 80 h after Peforelin or PMSG application Suckling period > 4 weeks: Gonadorelin6-D-Phe 56 - 58 h after Peforelin or PMSG application Suckling period 4 weeks: Gonadorelin6-D-Phe 72 h after Peforelin or PMSG application Suckling period 3 weeks: Gonadorelin6-D-Phe 78 - 80 h after Peforelin or PMSG application 1st AI 24 - 26 h after Gonadorelin6-D-Phe application 24 - 26 h after Gonadorelin6-D-Phe application 2nd AI 40 - 42 h after Gonadorelin6-D-Phe application 40 - 42 h after Gonadorelin6-D-Phe application * The preferred dose of Gonavet Veyx in gilts is 50 micrograms Gonadorelin[6-D-Phe]. However, the dose may be adjusted within the range of 50 - 75 micrograms to take into account farm-specific aspects or seasonal influences. The proposed time table should be strictly kept. ** The preferred dose of Gonavet Veyx in adult sows is 50 micrograms Gonadorelin[6-D-Phe]. However, the administration of 25 micrograms is also sufficient in case of sows with sow parity of more than 3 or during the mating period of September until May. The proposed time table should be strictly kept. 4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary None known.
Withdrawals	4.11 Withdrawal period(s) Cattle, pigs, horses Meat and offal: Zero days Cattle, horses Milk: Zero hours