Eprinex Pour-On 1Lt

Target species Beef and dairy cattle. Indications for use Indicated for treatment and control of the following parasites: Gastrointestinal Roundworms (Adult, L4 and Inhibited L4) Ostertagia ostertagi Cooperia spp. Gastrointestinal Roundworms (Adult and L4) Ostertagia spp. Cooperia oncophora Cooperia pectinata Cooperia punctata Cooperia surnabada Haemonchus placei Trichostongylus spp. Trichostrongylus axei Trichostrongylus colubriformis Bunostomum phlebotomum Nematodirus helvetianus Oesophagostomum radiatum Gastrointestinal roundworms (Adult) Ostertagia lyrata Oesophagostomum spp. Trichuris spp. Lungworms (Adult and L4) Dictyocaulus viviparus Warbles (parasitic stages) Hypoderma bovis H.lineatum Mange mites Chorioptes bovis Sarcoptes scabiei Lice Damalinia bovis (biting lice) Linognathus vituli (sucking lice) Haematopinus eurysternus (sucking lice) Solenopotes capillatus (sucking lice) While mite and louse numbers decline rapidly following treatment, due to the feeding habits of the parasites, in some cases several weeks may be required for complete eradication. Prolonged Activity Applied as recommended, the product controls reinfections with Dictyocaulus viviparus, Ostertagia spp. and Oesophagostomum radiatum for up to 28 days, Cooperia spp. and Trichostrongylus spp. for up to 21 days, and Haemonchus placei and Nematodirus helvetianus for up to 14 days. The following species are included within each of the relevant genera: Ostertagia ostertagi, O. lyrata, Cooperia oncophora, C. punctata, C. surnabada, Trichostrongylus axei, T. colubriformis. For best results use as part of a program to control both internal and external parasites of cattle based on the epidemiology of these parasites. Contra-indications This product is formulated only for topical application to beef and dairy cattle, including lactating dairy cattle. Do not use in other animal species. Do not administer orally or by injection. Do not apply to areas of the backline covered with mud or manure. Special warnings for each target species The details provided in the ‘Overdose’ section apply. Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy: - Too frequent and repeated use of anthelmintics from the same class, over an extended period of time. - Underdosing, which may be due to underestimation of bodyweight, misadministration of the product, or lack of calibration of the dosing device (if any). Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. To date no resistance to eprinomectin (a macrocyclic lactone) has been reported within the EU. However resistance to other macrocyclic lactones has been reported in parasite species in cattle within the EU. Therefore, use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics. Special precautions for use in animals Not to be used in other species; avermectins can cause fatalities in dogs. Special precautions to be taken by the person administering the product Operators should wear rubber gloves when applying the product. If accidental skin contact occurs, wash the affected area immediately with soap and water. If accidental eye exposure occurs, flush eyes immediately with water. Do not smoke, eat or drink while handling the product. Wash hands after use. Should clothing become contaminated, remove as soon as possible and launder before re-use. In the event of ingestion, wash out mouth with water and seek medical advice. Adverse reactions No undesirable effects have been identified when the product is used at the recommended dose rate. Use during pregnancy, lactation or lay May be used in dairy cattle during all stages of lactation. Studies have demonstrated a wide safety margin. Studies conducted at three times the recommended use level of 0.5 mg eprinomectin/kg body weight had no adverse effect on breeding performance of cows or bulls. Interactions No interactions with other medicaments and no other forms of interactions are known.