Endofluke 5Ltr

Target species Cattle & Sheep. Indications for use For the treatment of adult, immature and early immature stages of liver fluke (Fasciola hepatica) susceptible to triclabendazole. Contra-indications Do not use in animals known to be hypersensitive to the active substance. Special precautions for use in animals Care should be taken to avoid the following practices, because they increase the risk of development of resistance and could ultimately result in ineffective therapy: -Too frequent and repeated use of anthelmintics from the same class, over an extended period of time. Under dosing, which may be due to underestimation of bodyweight, misadministration of the product or lack of calibration of the dosing device (if any). Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. Resistance to triclabendazole has been reported in Fasciola hepatica in cattle and sheep.Therefore, the use of this product should be based on local (regional/farm) epidemiological information about susceptibility of the Fasciola hepatica and recommendations on how to limit further selection for resistance to anthelmintics. Care should be taken when dosing animals to avoid causing injury to the mouth and pharynx. Special Precautions to be taken by the person administering the product to animals When using, do not eat, drink or smoke. Wash splashes from eyes and skin immediately. Take off immediately any contaminated clothing. Wash hands and exposed skin before meals and after use. Other precautions The use of this product may have harmful effects on fish and aquatic invertebrates. Cattle and sheep must not have any access to the surface water such as streams, ponds or ditches within 7 days after treatment. When spreading manure from treated animals on arable lands, a safety distance of 10m to adjacent surface waters must be kept. Adverse reactions Occasionally, inflammation of the unpigmented skin, including the udder and the teats may occur after treatment in cattle exposed to intense sunshine. Use during pregnancy, lactation or lay The product is safe for use during pregnancy and lactation. However, the product is not permitted for use during lactation in animals producing milk for human consumption (see withdrawal periods). Interactions None known.