Bimectin Inection 250ml

Target species Cattle, sheep and pigs. Indications for use For the effective treatment and control of the following harmful parasites of cattle, sheep and pigs: Cattle: Gastrointestinal roundworms (adult and fourth-stage larvae): Ostertagia spp. (including inhibited O. ostertagi) Haemonchus placei Trichostrongylus axei T. colubriformis Cooperia spp. Bunostomum phlebotomum Oesophagostomum radiatum Strongyloides papillosus (adult) Nematodirus helvetianus (adult) N. spathiger (adult) Trichuris spp (adult). Lungworms (adult and fourth-stage larvae): Dictyocaulus viviparus Eye worms (adult): Thelazia spp. Warbles: Hypoderma bovis H. lineatum Mange mites: Psoroptes bovis Sarcoptes scabiei var. bovis Sucking lice: Linognathus vituli Haematopinus eurysternus Solenopotes capillatus May also be used as an aid in the control of the mange mite Chorioptes bovis and biting lice Damalinia bovis, but complete elimination may not occur. Persistent Activity Treatment at the recommended dose rate can control re-infection with Haemonchus placei and Cooperia spp. acquired up to 14 days after treatment, Ostertagia ostertagi and Oesophagostomum radiatum acquired up to 21 days after treatment and Dictyocaulus viviparus up to 28 days after treatment. To obtain optimal benefit from the persistent activity of the product for grazing animals, it is recommended that calves which are set-stocked in the first grazing season should be treated 3, 8 and 13 weeks after the day of turn-out. This can protect the animals from parasitic gastroenteritis and lungworm disease throughout the grazing season, provided they are set-stocked, all the calves included in the programme and that no untreated cattle are added to the pasture. Treated animals should always be monitored according to good husbandry practices. Sheep: Gastrointestinal roundworms (adult and fourth-stage larvae): Ostertagia circumcincta including inhibited larvae O. trifurcata Haemonchus contortus including inhibited larvae Trichostrongylus axei (adults) T. colubriformis and T. vitrinus (adults) Cooperia curticei Oesophagostomum columbianum O. venulosum (adults) Nematodirus filicollis Chabertia ovina Trichuris ovis (adults). Lungworms: Dictyocaulus filaria (adult and fourth-stage larvae) Protostrongylus rufescens (adults) Nasal Bots (all larval stages) Oestrus ovis Pigs: Gastrointestinal roundworms (adult and fourth-stage larvae): Ascaris suum Hyostrongylus rubidus Oesophagostomum spp. Strongyloides ransomi (adult and somatic larval stages) Lungworms: Metastrongylus spp. (adults) Lice: Haematopinus suis Mange mites: Sarcoptes scabiei var. suis Contra-indications Do not use in animals with known hypersensitivity to the active ingredient. Do not use by intramuscular or intravenous administration. Special warnings for each target species Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy: -Too frequent and repeated use of anthelmintics from the same class, over an extended period of time. -Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device. Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. Resistance to ivermectin has been reported in Teladorsagia circumcincta in sheep and Ostertagia ostertagi in cattle. Therefore, the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of these helminth species and recommendations on how to limit further selection for resistance to anthelmintics. Special precautions for use Special Precautions for use in animals The product has been formulated specifically for use in cattle, sheep and pigs. It should not be used in other species as severe adverse reactions, including fatalities in dogs, may occur. Special Precautions to be taken by the Person Administering the Product to Animals Take care to avoid self-administration: the product may cause local irritation and/or pain at the site of injection. Direct contact of the product with the skin should be kept to a minimum. Do not smoke or eat while handling the product. Wash hands after use. Other precautions When using the 250 ml and 500 ml pack sizes, use only automatic syringe equipment. For the 50 ml pack size, use of a multiple dose syringe is recommended. To refill the syringe, use of a draw off needle is recommended to avoid excessive broaching of the stopper. Adverse reactions Cattle: Transient discomfort has occasionally been observed in cattle following subcutaneous administration. A low incidence of soft tissue swelling at the injection site has been observed. Sheep: Discomfort, sometimes intense but usually transient, has been observed in some sheep immediately following subcutaneous administration. Pigs: Mild and transient discomfort has occasionally been observed in pigs following subcutaneous injection. All these reactions disappeared without treatment. Use during pregnancy, lactation or lay Pregnancy: The product can be administered to beef cows, sheep and pigs at any stage of pregnancy Lactation: Do not use in dairy cows or sheep producing milk for human consumption Do not use in non-lactating dairy cows or sheep within 60 days of calving/lambing. The product can be used in sows during lactation. Fertility: Fertility is not affected by administration of the product. Interactions The product can be used concurrently without adverse effects with foot and mouth disease vaccine or clostridial vaccine, given at separate injection sites.